2. Signaling Pathways
  3. Epigenetics
  4. Histone Demethylase
  5. KDM5 Isoform
  6. KDM5 Degrader

KDM5 Degrader

KDM5 Degrader (1):

Cat. No. Product Name Effect Purity
  • HY-175036
    YTHu78
    		Degrader
    YTHu78 is a KDM5B PROTAC-type degrader. YTHu78 induces KDM5B degradation via the ubiquitin-proteasome system and triggers apoptosis in MV-4-11 and MM.1S cell lines. YTHu78 exhibits significant antiproliferative activity against a variety of hematological cancer cell lines and can be used to study hematological cancers. (Pink: KDM5B ligand: (HY-116761); Blue: Thalidomide ligand: (HY-14658), Black + Pink: KDM5B ligand + linker: (HY-175145)).